In 1919, the NYS Genealogical and Biographical Society transcribed the records of the Reformed Protestant Dutch Church at the Owasco outlet in Fleming, Cayuga County, NY. Edited by Royden Woodward Vosburgh, I obtained copies of pages listing marriages from 1844 to 1850; a few from 1854, and 1861 to 1863. Fleming borders the northern edge of Scipio, so several names were of interest. It is difficult to find vital records from these years, so I hope you find one here that you have been seeking!
The Reverend A. B. Winfield performed these marriages:
Henry Farnam married Cornelia Adeline Darrow of Scipio on December 4, 1845.
John H. Smith married Jane Elizabeth Knox of Scipio on March 18, 1846.
Herman Macumber married Mrs. Margaret Knox of Scipio on October 14, 1846.
William De Groff of Fleming married Helen Holmes of Scipio on October 26, 1848.
David Keeles married Lydia Close of Scipio on December 3, 1850.
The Reverend S. R. Brown performed the marriage ceremony for Baxter Colvin of Cato and Miss Mary A. Knox of Scipio in June of 1854.
These weddings were performed by the Reverend John Garretson:
John Graham of Fishkill, Dutchess County, NY married Phebe A. Hasbrook of Scipio, Cayuga County, NY on September 18, 1861.
George W. Miller of Scipio was married to Celia Stocker also of Scpio on August 28, 1863.